© 2015 American Association of Public Health Dentistry. Objective: The aims of this study were to examine dentists’ recommendations for in-office fluoride to patients and identify dentists’ characteristics associated with these recommendations. Study Design and Setting: The study was conducted using a cross-sectional questionnaire survey in Japan. The survey queried dentists (n = 282) in outpatient dental practices affiliated with the Dental Practice-based Research Network Japan (JDPBRN). This network aims to assist dentists in investigating research questions and sharing their experience and expertise. Results: The responses were obtained by 189 dentists (67 percent). Among valid response, 54 percent of dentists (n = 98) recommend in-office fluoride to more than 50 percent of their patients aged 6-18 years and 15 percent (n = 29) recommended this care tomore than 50 percent of their patients aged over 18 years.Multiple logistic regression analysis suggested that factors associated with the percentage of patients who are recommended in-office fluoride included patient’s interest in caries prevention and dentist’s belief in the effectiveness of caries risk assessment. Conclusions: Dentist practice patterns for recommending in-office fluoride vary widely. Recommendation was significantly related to having a higher percentage of patients interested in caries prevention and to the dentist’s belief about the effectiveness of caries risk assessment.