The epidemiological, etiological and clinical perspectives of many skin disorders allow us to understand the current global aspects. Studies suggest that patients of skin disorders follow social withdrawal and limiting their occupational activities which further lead to economic and psychological burden and sometime depression. Many pathophysiological mechanisms were reported to contribute in clinical manifestations of many cutaneous diseases. Current treatments for skin disorders include use of surgical sections phototherapy, systemic and topical medications; however, each of them is associated with certain limitations. Prominently, the ongoing therapeutic strategies have been reported to be present with adverse reactions, low efficacy and often, drug resistance complicates the disease status, emerging as one of the most diminishing situations. The emerging in vitro, in vivo and clinical studies indicate that herbal plants have been used for their immense potential against almost every kind of skin disorder. Importantly, the herbal plants were identified to contain alkaloids, phenolics, glycosides, terpenes, lignans, quinones, flavonoids, tannins, coumarins curcuminoids etc. Numerous herbal medicines and plant-derived products show promising credibility for the treatment and prevention in many skin disorders. The herbal medicines are of great interest due to their beneficial aspects in terms of safety, efficacy and fewer side effects. Interestingly, the herbal medicines and their bioactive ingredients have long been investigated for their antibacterial, anti-dermatophytic, antioxidant, anti-inflammatory, anti-proliferative, and chemoprotective against melanoma and non-melanoma skin cancers, dermatophytosis, atopic dermatitis, psoriasis, and acne. The current situation demands more intense research for getting approval of many herbal derived products in combating the skin disorders.