Herpes simplex viruses



  • Herpes simplex virus (HSV) infections of humans have been documented since the advent of writing. Genital herpes was described in Sumerian literature (1). Greek scholars, particularly Hippocrates, used the word “herpes, " meaning to creep or crawl, to describe the spreading nature of skin lesions (2). Herodotus associated mouth ulcers and lip vesicles with fever and called it “herpes febrilis.” Many of these original observations likely emanated from Galen’s deduction that the appearance of lesions was an attempt by the body to rid itself of evil humors, leading to the description “herpes excretins.”.
  • Digital Object Identifier (doi)

    International Standard Book Number (isbn) 13

  • 9781555819422
  • Start Page

  • 415
  • End Page

  • 445