Modulation of neurophysiological auditory processing measures by bilateral transcranial direct current stimulation in schizophrenia

Academic Article

Abstract

  • This study used bilateral transcranial direct current stimulation (tDCS) to target neural generators of auditory Mismatch Negativity (MMN) and oddball P300 in schizophrenia patients. tDCS was applied to the pre-frontal cortex in a parallel between-group design. There was a significant main effect of stimulation resulting in modulation of MMN amplitude. This effect was mainly driven by a non-significant, but large, effect-size decrease in MMN amplitude with anodal stimulation. This is the first study to demonstrate that tDCS is able to engage and modulate an EEG-based auditory processing measure in schizophrenia.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Dunn W; Rassovsky Y; Wynn JK; Wu AD; Iacoboni M; Hellemann G; Green MF
  • Start Page

  • 189
  • End Page

  • 191
  • Volume

  • 174
  • Issue

  • 1-3