OBJECTIVE: Resilience is broadly defined as the ability to respond adaptively to challenges or adversity. It is unclear which clinical and cognitive factors are most closely related to resilience. Also, the dimensions that comprise resilience may differ among different groups, such as those who are homeless. The purpose of this study was to understand the relationships between resilience and clinical, cognitive, and functional variables among homeless veterans and to determine independent predictors of resilience. METHOD: One hundred homeless veterans completed measures of resilience, defeatist beliefs, negative symptoms, psychotic and mood symptoms, social and nonsocial cognition, and community functioning. We examined associations between resilience and clinical, cognitive, and functional measures. We performed regression analyses to determine independent contributions of the variables to resilience. RESULTS: Resilience was correlated with negative symptoms, defeatist beliefs, depression/anxiety symptoms, and social cognition. There were no significant correlations with nonsocial cognition or psychotic symptoms. Stepwise multiple linear regression showed that defeatist beliefs, motivational negative symptoms, expressive negative symptoms, and depression/anxiety symptoms made independent contributions. Resilience was correlated with community functioning in the domains of work, independent living, and social and family relationships. History of psychosis moderated the relationship between resilience and defeatist beliefs, which was stronger in those who had experienced psychosis. CONCLUSIONS AND IMPLICATIONS FOR PRACTICE: These findings suggest that resilience is an important construct to consider in homeless veterans, is related to other clinical factors such as defeatist beliefs and negative symptoms, and could be a valuable treatment target with the goal of improving functioning. (PsycINFO Database Record (c) 2019 APA, all rights reserved).