In vitro activities of eravacycline and other antimicrobial agents against human mycoplasmas and ureaplasmas

Academic Article

Abstract

  • We performed in vitro susceptibility testing for eravacycline in comparison to 4 other antimicrobials against 10 Mycoplasma genitalium, 40 Mycoplasma hominis, 44 Mycoplasma pneumoniae, 20 Ureaplasma parvum, and 20 Ureaplasma urealyticum isolates. All eravacycline MICs were ≤0.25 μg/ml, except that for one isolate of M. genitalium, for which the MIC was 2 μg/ml. Eravacycline was markedly more potent than tetracycline, azithromycin, moxifloxacin, and clindamycin against all isolates tested, which included 37 macrolide, tetracycline, and/or fluoroquinoloneresistant organisms.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Waite KB; Crab DM; Xiao L; Duff LB; Leal SM
  • Volume

  • 64
  • Issue

  • 8