A very rare case of eyelid metastasis originating from lung adenocarcinoma

Academic Article


  • Purpose: To report a very rare eyelid mass confirmed to be a metastasis from lung adenocarcinoma. Methods: A 68-year-old man had a two-month history of a large nodule in the right upper eyelid. He was a known case of lung adenocarcinoma since 2¬†years without a history of systemic metastasis. He underwent further investigations including orbital imaging and biopsy of the lesion. Results: Biopsy and immunohistochemical evaluations of the eyelid lesion revealed a moderate to poorly differentiated adenocarcinoma, a similar histology to the lung lesion. Conclusions: Metastatic involvement of the eyelids is rarely seen; specifically, those associated with lung adenocarcinoma as the source have been reported extremely rare. Eyelid metastases present with various and non-specific clinical features, and therefore biopsy of suspicious or recurrent lesions is highly recommended to rule out such malignant processes.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Tavakoli M; Assadi M; Seifi MH; Behdad B; Salour H
  • Start Page

  • 743
  • End Page

  • 746
  • Volume

  • 36
  • Issue

  • 5