Patterns of Cerebellar Connectivity with Intrinsic Connectivity Networks in Autism Spectrum Disorders

Academic Article

Abstract

  • There is growing evidence of altered connectivity in autism spectrum disorders (ASD) between the cerebellum and cortex. Three intrinsic connectivity networks (ICNs) are especially important to cognitive processing in ASD: the default mode network (DMN), executive control network (ECN), and salience networks (SNs). The goal of this study was to compare resting-state functional connectivity between the cerebellum and the DMN, ECN, and SN in ASD and typically developing children (n = 74, ages 7–12 years). Children with ASD showed stronger connectivity between the ventral DMN and left cerebellar lobules I–IV. No meaningful relationships were observed between ICN-cerebellar functional connectivity and ASD symptoms. These results suggest that the cerebellum contributes to altered network connectivity in ASD.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Bednarz HM; Kana RK
  • Start Page

  • 4498
  • End Page

  • 4514
  • Volume

  • 49
  • Issue

  • 11