Septic shock and multi-organ failure in HIV infection-'sepsis tuberculosa gravissima'

Academic Article


  • A profoundly immunosuppressed HIV-infected man developed sepsis syndrome with multi-organ failure. A septic screen failed to identify a bacterial or fungal cause and despite empirical treatment for these pathogens the patient remained unwell. Investigations revealed disseminated tuberculosis. With specific anti-tuberculosis therapy the patient rapidly recovered. Although most cases of sepsis syndrome in HIV-infected patients are due to bacteria, tuberculosis should be added to the differential diagnosis of this presentation.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Ferrand RA; Herman J; Elgalib A; Cartledge J; Miller RF
  • Start Page

  • 562
  • End Page

  • 564
  • Volume

  • 17
  • Issue

  • 8