Importance of tissue sampling, laboratory methods, and patient characteristics for detection of Pneumocystis in autopsied lungs of non-immunosuppressed individuals

Academic Article


  • To understand the epidemiological significance of Pneumocystis detection in a lung tissue sample of non-immunosuppressed individuals, we examined sampling procedures, laboratory methodology, and patient characteristics of autopsy series reported in the literature. Number of tissue specimens, DNA-extraction procedures, age and underlying diagnosis highly influence yield and are critical to understand yield differences of Pneumocystis among reports of pulmonary colonization in immunocompetent individuals.
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Vargas SL; Ponce C; Bustamante R; Calderón E; Nevez G; De Armas Y; Matos O; Miller RF; Gallo MJ
  • Start Page

  • 1711
  • End Page

  • 1716
  • Volume

  • 36
  • Issue

  • 10