Feedback processing in adolescents with prenatal cocaine exposure: an electrophysiological investigation

Academic Article

Abstract

  • © 2018 Taylor & Francis. Impaired cognitive control is a consequence of cocaine exposure. Difficulty with feedback processing may underlie this impairment. We examined neural correlates of feedback processing using event-related potentials (ERPs) in 49 prenatally cocaine-exposed (PCE) and 34 nondrug exposed (NDE) adolescents. Adolescents performed a reward-feedback task with win/no-win feedback in a chance-based task. We investigated amplitude and latency of the feedback-related negativity (FRN) and P300 ERP components and source-based estimates elicited during feedback processing. PCE adolescents had smaller P300 amplitudes for no-win feedback, and source analysis in the P300 time window revealed differences between groups localized to the dorsal anterior cingulate cortex.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 22176496
  • Author List

  • Morie KP; Wu J; Landi N; Potenza MN; Mayes LC; Crowley MJ
  • Start Page

  • 183
  • End Page

  • 197
  • Volume

  • 43
  • Issue

  • 3