Four "lessons learned" while implementing a multi-site caries prevention trial

Academic Article

Abstract

  • As the number of dental-related randomized clinical trials (RCTs) increases, there is a need for literature to help investigators inexperienced in conducting RCTs design and implement studies. This commentary describes four "lessons learned" or considerations important in the planning and initial implementation of RCTs in dentistry that, to our knowledge, have not been discussed in the general dental literature describing trial techniques. These considerations are a) preparing or securing a thorough systematic review; b) developing a comprehensive set of study documents; c) designing and testing multiple recruitment strategies; and d) employing a run-in period prior to enrollment. Attention to these considerations in the planning phases of a dental RCT can help ensure that the trial is clinically relevant while also maximizing the likelihood that its implementation will be successful. © 2010 American Association of Public Health Dentistry.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Bader JD; Robinson DS; Gilbert GH; Ritter AV; Makhija SK; Funkhouser KA; Amaechi BT; Shugars DA; Laws R
  • Start Page

  • 171
  • End Page

  • 175
  • Volume

  • 70
  • Issue

  • 3