Associations of neighborhood area level deprivation with the metabolic syndrome and inflammation among middle- and older- age adults.

Academic Article


  • BACKGROUND: The study examines the association of neighborhood socioeconomic deprivation and metabolic syndrome with inflammation. METHODS: The analysis included 19, 079 black and white participants from the REasons for Geographic And Racial Differences in Stroke Study who were age > 45 years at baseline. Logistic regression examined whether neighborhood deprivation was associated with increased odds of METS and CRP-MetS. RESULTS: Among black adults, residing in the most deprived neighborhoods was associated with increased odds of obesity (p < .01), lower HDL (p < .001), high blood pressure (p < .01), elevated fasting glucose (p < .001), inflammation (p < .01), and CRP-MetS (p < .001). Among white adults, neighborhood deprivation was associated with higher waist circumference (p < .001), lower HDL (p < .001), higher triglycerides (p < .01), higher glucose (p < .001), higher BMI (p < .0001), higher blood pressure (p = .01), METS (p < .001), inflammation (p < .01) and CRP-MetS (p < .001). CONCLUSIONS: These findings highlight the role of neighborhood socioeconomic deprivation on METS and CRP-MetS for black and white adults. Interventions tailored to address the contextual effects of deprived neighborhoods may reduce the observed neighborhood disparities.
  • Published In

  • BMC Public Health  Journal
  • Keywords

  • African Americans, Aged, Blood Glucose, C-Reactive Protein, Cholesterol, HDL, Dyslipidemias, European Continental Ancestry Group, Female, Humans, Hypertension, Inflammation, Logistic Models, Male, Metabolic Syndrome, Middle Aged, Obesity, Residence Characteristics, Social Class, Triglycerides, Waist Circumference
  • Digital Object Identifier (doi)

    Author List

  • Keita AD; Judd SE; Howard VJ; Carson AP; Ard JD; Fernandez JR
  • Start Page

  • 1319
  • Volume

  • 14