Synthesis of the Rheb and K-Ras4B GTPases

Academic Article

Abstract

  • Now available! Farnesylated and carboxymethylated Rheb (see picture) and K-Ras4B GTPases were synthesized in useful amounts by a combination of expressed protein ligation and solid-phase lipopeptide synthesis. The functionality of the proteins was proven by biochemical, biophysical, and cell-based investigations. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
  • Published In

  • Angewandte Chemie  Journal
  • Digital Object Identifier (doi)

    Author List

  • Chen YX; Koch S; Uhlenbrock K; Weise K; Das D; Gremer L; Brunsveld L; Wittinghofer A; Winter R; Triola G
  • Start Page

  • 6090
  • End Page

  • 6095
  • Volume

  • 49
  • Issue

  • 35