Allocentric spatial neglect with posterior cortical atrophy

Academic Article


  • © , This work was authored as part of the Contributor’s official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 USC. 105, no copyright protection is available for such works under US Law. Patients with posterior cortical atrophy (PCA) have been reported to have neglect in the egocentric/ body-centered reference frame. This report describes a woman with PCA who had a right-sided stimulus-based form of allocentric visual neglect on cancellation, reading, and drawing tests. Her brain imaging revealed left parietal atrophy. The pathophysiology of this disorder may be related to an impairment of the ventral “what” stream’s ability to interact with the dorsal “where” stream that mediates the allocation of spatial attention, or a deficit in the systems that allocate contralateral focal attention. Further research is needed to better understand the mechanisms of this disorder and to optimally treat it.
  • Authors

    Published In

  • Neurocase  Journal
  • Digital Object Identifier (doi)

    Author List

  • Zilli EM; Heilman KM
  • Start Page

  • 190
  • End Page

  • 197
  • Volume

  • 21
  • Issue

  • 2