© Oxford University Press, 2009. All rights reserved. One of the most dramatic forms of confabulation is anosognosia. In spite of having a profound neurological deficit, patients with this disorder tell the examiner that they have no problems. In addition, when patients with anosognosia are asked questions about their abilities and disabilities their answers might be confabulatory. This chapter explores why patients with hemispheric dysfunction might be unaware of their disabilities.