Genome sequence analysis of Ebola virus in clinical samples from three British healthcare workers, august 2014 to march 2015

Academic Article

Abstract

  • © 2015, European Centre for Disease Prevention and Control (ECDC). All rights reserved. We determined complete viral genome sequences from three British healthcare workers infected with Ebola virus (EBOV) in Sierra Leone, directly from clinical samples. These sequences closely resemble those previously observed in the current Ebola virus disease outbreak in West Africa, with glycoprotein and polymerase genes showing the most sequence variation. Our data indicate that current PCR diagnostic assays remain suitable for detection of EBOV in this epidemic and provide confidence for their continued use in diagnosis.
  • Published In

  • Eurosurveillance  Journal
  • Digital Object Identifier (doi)

    Author List

  • Bell A; Lewandowski Kuiama K; Myers R; Wooldridge D; Aarons E; Simpson A; Vipond R; Jacobs M; Gharbia S; Zambon M
  • Volume

  • 20
  • Issue

  • 20