Ruthenium complexes of six-electron-donor NUPHOS-Type diphosphines: Highly selective catalysts for the hydrocarboxylation of terminal alkynes

Academic Article

Abstract

  • The ruthenium-p-cymene complexes [p-cymene)Ru(1,2,3,4-Me 4 -NUPHOS)Cl][SbF 6 ] and [(p-cymene)Ru(1,4-Et 2 -2,3-cyclo-C 6 H 8 -NUPHO S)Cl][SbF 6 ] were prepared by reaction of [(p-cymene)RuCl 2 ] 2 with the corresponding NUPHOS diphosphine in the presence of NaSbF 6 . The crystal structures of these complexes were determined by single-crystal X-ray crystallography. The highly regio- and stereoselective addition of benzoic acid to phenylacetylene using catalysts based on NUPHOS was studied. The higher cis-to-trans ratios for anti-Markovnikov addition of benzoic acid to terminal alkynes with NUPHOS-based catalysts compared with their biaryl-based counterparts.
  • Authors

    Published In

  • Organometallics  Journal
  • Digital Object Identifier (doi)

    Author List

  • Doherty S; Knight JG; Rath RK; Clegg W; Harrington RW; Newman CR; Campbell R; Amin H
  • Start Page

  • 2633
  • End Page

  • 2644
  • Volume

  • 24
  • Issue

  • 11