Synthesis of a new class of 1,4-bis(diphenylphosphino)-1,3-butadiene bridged diphosphine, NUPHOS, via zirconium-mediated reductive coupling of alkynes and diynes: Applications in palladium-catalyzed cross-coupling reactions

Academic Article

Abstract

  • The synthesis of a new class of 1,4-bis(diphenylphosphino)-1,3-butadiene was discussed. Catalyst mixtures based on 1,2,3,4-Ph 4 -NUPHOS were found to be superior to those based on BINAP, with activities of 6900 and 260 (mol of product) (mol of palladium) -1 h -1 respectively. The applications in palladium catalyzed cross-coupling reactions were also discussed.
  • Authors

    Published In

  • Organometallics  Journal
  • Digital Object Identifier (doi)

    Author List

  • Doherty S; Robins EG; Nieuwenhuyzen M; Knight JG; Champkin PA; Clegg W
  • Start Page

  • 1383
  • End Page

  • 1399
  • Volume

  • 21
  • Issue

  • 7