Rhodium complexes of (R)-Me-CATPHOS and (R)-(S)-JOSIPHOS: highly enantioselective catalysts for the asymmetric hydrogenation of (E)- and (Z)-β-aryl-β-(enamido)phosphonates

Academic Article

Abstract

  • Rhodium complexes of (R)-Me-CATPHOS and (R)-(S)-JOSIPHOS form a complementary pair of catalysts for the highly efficient asymmetric hydrogenation of a selection of (E)- and (Z)-β-aryl-β-(enamido)phosphonates, respectively, in the majority of cases giving excellent yields and ee's in excess of 99%; the highest to be reported for this class of substrate. © 2009 Elsevier Ltd. All rights reserved.
  • Authors

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    Digital Object Identifier (doi)

    Author List

  • Doherty S; Knight JG; Bell AL; El-Menabawey S; Vogels CM; Decken A; Westcott SA
  • Start Page

  • 1437
  • End Page

  • 1444
  • Volume

  • 20
  • Issue

  • 12