Genome-wide scan for Parkinson's disease: The GenePD study

Academic Article

Abstract

  • A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine β-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.
  • Published In

  • Neurology  Journal
  • Digital Object Identifier (doi)

    Author List

  • DeStefano AL; Golbe LI; Mark MH; Lazzarini AM; Maher NE; Saint-Hilaire M; Feldman RG; Guttman M; Watts RL; Suchowersky O
  • Start Page

  • 1124
  • End Page

  • 1126
  • Volume

  • 57
  • Issue

  • 6