The stability and short-term fluctuation in serum oxytocinase activity in pregnancy.

Academic Article

Abstract

  • Maternal serum samples obtained from 123 normal pregnant women between 28 and 40 weeks gestation were analysed for oxytocinase (EC 3.4.11.3) activity using s-benzyl-1-cysteine-4-nitroanilide as substrate. Oxytocinase activity was found to be stable at varying temperatures, with a mean co-efficient of variation of 5.0%. The short-term fluctuation of oxytocinase activity had a mean coefficient of variation of 3.6%. There is no suggestion of a "pulsatile" release of oxytocinae from its placental origin.
  • Keywords

  • Aminopeptidases, Cystinyl Aminopeptidase, Female, Humans, Placenta, Pregnancy, Time Factors
  • Author List

  • Edebiri AA; Mack DS; McDonald DJ; Philips J
  • Start Page

  • 331
  • End Page

  • 335
  • Volume

  • 28
  • Issue

  • 4