Effect of positive end-expiratory pressure on dynamic respiratory compliance in neonates.

Academic Article


  • A simplified method of determining dynamic respiratory compliance (C dyn) in the newborn is described. Studies were performed during mechanical ventilation on 24 infants with respiratory distress syndrome (RDS) and 6 infants without RDS. Cdyn was evaluated at pressure settinghs of 20/0, 25/5 and 30/10 cm H2O. Significant decreases (p < 0.05) in Cdyn were noted with each increase in end-expiratory pressure setting. The values for Cdyn in RDS patients obtained by this method closely approximated previously published data for lung compliance in babies with RDS. This simple and reproducible method may be useful in following the course of illness in infants with RDS.
  • Published In


  • Forced Expiratory Flow Rates, Humans, Infant, Low Birth Weight, Infant, Newborn, Intermittent Positive-Pressure Ventilation, Lung Compliance, Respiratory Distress Syndrome, Newborn
  • Digital Object Identifier (doi)

    Author List

  • Philips JB; Beale EF; Howard JE; Jaeger MJ; Eitzman DV
  • Start Page

  • 270
  • End Page

  • 275
  • Volume

  • 38
  • Issue

  • 5-6