Preservation of Biospecimens at Ambient Temperature: Special Focus on Nucleic Acids and Opportunities for the Biobanking Community.

Academic Article


  • Several approaches to the preservation of biological materials at ambient temperature and the relative impact on sample stability and degradation are reviewed, with a focus on nucleic acids. This appraisal is undertaken within the framework of biobank risk, quality management systems, and accreditation, with a view to assessing how best to apply ambient temperature sample storage to ensure stability, reduce costs, improve handling logistics, and increase the efficiency of biobank procedures.
  • Published In


  • Biological Specimen Banks, Nucleic Acids, Preservation, Biological, Quality Control, Temperature
  • Digital Object Identifier (doi)

    Author List

  • Muller R; Betsou F; Barnes MG; Harding K; Bonnet J; Kofanova O; Crowe JH; International Society for Biological and Environmental Repositories (ISBER) Biospecimen Science Working Group
  • Start Page

  • 89
  • End Page

  • 98
  • Volume

  • 14
  • Issue

  • 2