Effectiveness of antiretroviral therapy among HIV-infected children in sub-Saharan Africa.

Academic Article


  • Assessment of antiretroviral treatment programmes for HIV-infected children in sub-Saharan Africa is important to enable the development of effective care and improve treatment outcomes. We review the effectiveness of paediatric antiretroviral treatment programmes in sub-Saharan Africa and discuss the implications of these findings for the care and treatment of HIV-infected children in this region. Available reports indicate that programmes in sub-Saharan Africa achieve treatment outcomes similar to those in North America and Europe. However, progress in several areas is required to improve the care of HIV-infected children in sub-Saharan Africa. The findings emphasise the need for low-cost diagnostic tests that allow for earlier identification of HIV infection in infants living in sub-Saharan Africa, improved access to antiretroviral treatment programmes, including expansion of care into rural areas, and the integration of antiretroviral treatment programmes with other health-care services, such as nutritional support.
  • Authors

    Published In


  • Adolescent, Africa South of the Sahara, Anti-HIV Agents, Child, Child, Preschool, Drug Therapy, Combination, Female, HIV Infections, HIV-1, Humans, Infant, Male, National Health Programs, Patient Compliance, Reverse Transcriptase Inhibitors, Treatment Outcome
  • Digital Object Identifier (doi)

    Pubmed Id

  • 23979604
  • Author List

  • Sutcliffe CG; van Dijk JH; Bolton C; Persaud D; Moss WJ
  • Start Page

  • 477
  • End Page

  • 489
  • Volume

  • 8
  • Issue

  • 8