A fluorescent modification of adenosine triphosphate with activity in enzyme systems: 1,N 6 -ethenoadenosine triphosphate.

Academic Article

Abstract

  • A new, highly fluorescent adenosine triphophate (ATP) analog, 1,N(6) ethenoadenosine triphosphate, has been synthesized. Its fluorescence properties, including the long fluorescence lifetime and the possibility of detection at very low concentrations, in conjunction with its activity in the representative enzyme systems here reported, make it a valuable probe of enzymic mechanism and structure.
  • Published In

  • Science  Journal
  • Keywords

  • Adenosine Diphosphate, Adenosine Triphosphate, Fluorescence, Hexokinase, Imidazoles, Muscles, Phosphofructokinase-1, Pyruvate Kinase, Spectrum Analysis, Yeasts
  • Author List

  • Secrist JA; Barrio JR; Leonard NJ
  • Start Page

  • 646
  • End Page

  • 647
  • Volume

  • 175
  • Issue

  • 4022