Kinetics for the acid-catalyzed hydrolysis of purine and cytosine 2'- deoxy-4'-thionucleosides

Academic Article

Abstract

  • Hydrolysis of adenine, guanine and cytosine 2'-deoxy-4'-thionucleosides in aqueous acid has been followed by HPLC. Stability of the compounds and mechanisms of hydrolysis are discussed in comparison with those of the corresponding native 2'-deoxynucleosides.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 11308688
  • Author List

  • Elzagheid MI; Oivanen M; Walker RT; Secrist JA
  • Start Page

  • 181
  • End Page

  • 186
  • Volume

  • 18
  • Issue

  • 2