Photochemical Cleavage of Benzylic C-N Bond to Release Amines

Academic Article

Abstract

  • © 2016 American Chemical Society. The 3-(diethylamino)benzyl (DEABn) group has been studied for releasing primary, secondary, and tertiary amines by direct photochemical breaking of the benzylic C-N bond. While photochemical release of primary and secondary amines provides high yields in methanol, release of tertiary amines in MeCN/water can improve yields and reduce the undesired dealkylation side reaction.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Wang P; Devalankar DA; Lu W
  • Start Page

  • 6195
  • End Page

  • 6200
  • Volume

  • 81
  • Issue

  • 15