© 2018, Springer International Publishing AG, part of Springer Nature. Cardiac rehabilitation provides comprehensive secondary prevention services and improves outcomes among patients with coronary heart disease, systolic heart failure, and other cardiac rehabilitation indications. Worldwide, cardiac rehabilitation services are underutilized. Underutilization is more common among women than in men. This chapter reviews barriers to referral, enrollment, and adherence among women and potential interventions to improve women’s participation in cardiac rehabilitation. Gender similarities and differences in clinical, behavioral, and health outcomes of cardiac rehabilitation are addressed, and gaps in the evidence base are discussed, pointing to areas of future research.