There is a lack of consensus on the effects of vibration therapy on bone outcome measures. Vibration is a mechanical stimulus and can produce mechanical loading on bone. Similar to site-specific effects of
mechanical loading on bone, vibration therapy can also produce site-specific effects. Notably, skeletal effects of vibration therapy could depend on the degree of vibration signal that is received by respective
skeletal sites. Thus, vibration transmissibility can dictate, in part, effects of vibration therapy on bone outcome measures. Factors at various levels such as the type of vibration, type of population receiving vibration, and their interaction could affect vibration transmission. In addition, vibration amplitude, vibration frequency, joint position, body posture, resonance frequency of skeletal sites, tissue composition of human body including bone geometry can affect vibration transmission across the human body. The main aim of this review is to summarize the published evidence of various factors that affect vibration transmission which will help to inform future evidence based vibration therapy protocols for skeletal rehabilitation in various populations.