Immunohistochemical localization of protein phosphatase isoforms in the rat cerebellum

Academic Article

Abstract

  • Protein phosphatase isoforms, PP1γ1, PP1δ, PP1α and PP2A (α and/or β), were immunohistochemically localized in the rat cerebellum. Purkinje cell perikarya, dendrites and spines were very PP1γ1 immunoreactive. PP1δ and PP1α were perinuclear in all neurons, PP1α also revealed a new cell type and PP2A was homogeneous in Purkinje cell soma and large dendrites. PP1γ1 seems to be dominant for dephosphorylation at the dendritic synapses of Purkinje cells. © 1995.
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Hashikawa T; Nakazawa K; Mikawa S; Shima H; Nagao M
  • Start Page

  • 133
  • End Page

  • 136
  • Volume

  • 22
  • Issue

  • 1