Rapid and sensitive detection of respiratory virus molecular signatures using a silver nanorod array SERS substrate

Academic Article

Abstract

  • A spectroscopic assay based on surface enhanced Raman scattering (SERS) using silver nanorod array substrates has been developed that allows for rapid detection of trace levels of viruses with a high degree of sensitivity and specificity. This novel SERS assay can detect spectral differences between viruses, viral strains, and viruses with gene deletions in biological media. The method provides rapid diagnostics for detection and characterization of viruses generating reproducible spectra without viral manipulation. © 2006 American Chemical Society.
  • Authors

    Published In

  • Nano Letters  Journal
  • Digital Object Identifier (doi)

    Pubmed Id

  • 23792243
  • Author List

  • Shanmukh S; Jones L; Driskell J; Zhao Y; Dluhy R; Tripp RA
  • Start Page

  • 2630
  • End Page

  • 2636
  • Volume

  • 6
  • Issue

  • 11