Laboratory studies of biostimulation are predominantly of Eastern Block origin and for the most part are confined to measurements of DNA, RNA and protein synthesis in E. coli, yeasts and transformed mammalian cells. Few of these studies have compared the effects induced by coherent versus incoherent sources and fewer provide sufficient details of the exposure regime to enable the work to be repeated. We, like many other laboratories, found the published claims unconvincing. Given our scepticism we have undertaken a series of pilot experiments in an attempt to highlight possible sources of error in previous studies. This paper reports our results and is an attempt to promote further discussion.