Histocompatibility antigens controlled by the I region of the murine H-2 complex: II. KID Region compatibility is not required for I-region cell-mediated lymphocytotoxicity*

Academic Article


  • In the cell-mediated lymphocytotoxicity assay, A.TH effector cells sensitized to A.TL lymphocytes lyse not only A.TL but also C3H/HeJ and B10.A(4R) targets. Similarly, B10.T(6R) anti-B10.AQR effector cells lyse B10.BR and B10.BYR target cells in addition to B10.AQR cells. These findings indicate that for CML to occur across the I A region barrier, compatibility at K or D regions is not required. © American Society for Clinical Pathology.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 8555453
  • Author List

  • Klein J; Chiang CL; Hauptfeld V
  • Start Page

  • 450
  • End Page

  • 454
  • Volume

  • 145
  • Issue

  • 2