Avidin-biotin immunohistochemical staining for fibronectin was used to study 17 aphahic intraocular lens implanted globes and 12 explanted intraocular lenses. Fibronectin was identified as a component of acellular pseudophakic membranes and was also observed within lens epithelial cells and macrophages. © 1992, American Society of Cataract and Refractive Surgery. All rights reserved.