Objectives: To conduct a systematic review of scientific reports related to diet and cancer survivorship published since the 2006 American Cancer Society's Guide for Informed Choices on Nutrition and Physical Activity During and After Cancer Treatment and to integrate these findings into a consistent message that can be delivered by nurses in hopes of improving the health and well-being of cancer survivors. Data Sources: Journal articles. Conclusion: Cancer survivors represent a growing population at high risk for recurrence and other co-morbidities. Evidence continues to accumulate regarding the importance of weight management and a healthful diet (plant-based, low saturated fat) in improving the overall health and promoting disease-free and overall survival in this population. Implications for Nursing Practice: Cancer survivors are eager for nutrition information and nurses are well-positioned to guide them regarding the importance of weight management and healthy food choices. © 2008 Elsevier Inc. All rights reserved.