Hepatic arterial infusion chemotherapy for cancer of the liver

Academic Article


  • Hepatic artery infusion chemotherapy (HAIC) provides objective palliation for unresectable primary and secondary liver neoplasms. By utilizing HAIC rather than systemic chemotherapy, a greater concentration of the chemotherapeutic agent(s) within the liver is achieved with a comparative decrease in toxic side effects. A review of pertinent literature disclosed response rates of 50–71% associated with the administration of 5‐fluorouracil (5‐FU) and 5‐fluoro‐2‐deoxyuridine (5‐FUDR) via the hepatic artery, whereas response rates of 0–25% have been tabulated for systemic chemotherapy. Copyright © 1980 Wiley‐Liss, Inc., A Wiley Company
  • Published In

    Digital Object Identifier (doi)

    Author List

  • Bland KI; Knutson CO; Max MH
  • Start Page

  • 253
  • End Page

  • 258
  • Volume

  • 13
  • Issue

  • 3