Three examples of a new class of retinoic acid analogs (retinoids) were synthesized. These retinoids contain a dimethylene bridge to maintain a 6-s-cis conformation of the terminal double bonds, which is preferred in the major conformation of the natural compound. The1H and13C NMR spectra were assigned for 22 new compounds, including retinoid E/Z isomers (all-E, 13Z, 9Z) and selected intermediates. The assignments were based upon long-range1H-13C heteronuclear 2D experiments. © 1999 John Wiley & Sons, Ltd.