Speed of processing training in middle-aged and older breast cancer survivors (SOAR): results of a randomized controlled pilot.

Academic Article

Abstract

  • PURPOSE: Cognitive changes are common among breast cancer survivors. There is limited evidence to guide management of cognitive changes. This randomized controlled pilot evaluated the preliminary efficacy of a speed of processing (SOP) training among middle-aged and older breast cancer survivors. METHODS: Sixty breast cancer survivors  with self-reported cognitive changes were recruited to the SOAR study. Participants were randomized to either a home-based SOP training (n = 30) or no-contact control group (n = 30). Primary outcomes were SOP (Useful Field of View Test®), and executive function (NIH Toolbox Cognition Battery). Neuropsychological assessments were completed at baseline, 6 weeks, and 6 months post study entry. Data were analyzed using repeated measures t tests, analysis of covariance, and sensitivity analyses. RESULTS: SOP training resulted in improvement in objective measures of SOP and executive function. Immediate (6 week) posttest and 6-month follow-up demonstrated large SOP training effects over time. Large representation of African American women (51.2%) and 96% retention in the SOAR study add to study strengths. CONCLUSION: Home-based SOP training shows promise for remediating cognitive changes following breast cancer treatment, particularly improved SOP, and executive function.
  • Published In

    Keywords

  • Aging, Breast cancer survivors, Cognitive changes, Cognitive impairment, Speed of processing interventions
  • Digital Object Identifier (doi)

    Author List

  • Meneses K; Benz R; Bail JR; Vo JB; Triebel K; Fazeli P; Frank J; Vance DE
  • Start Page

  • 259
  • End Page

  • 267
  • Volume

  • 168
  • Issue

  • 1