New formulas for the calculation of effective renal plasma flow

Academic Article


  • Estimation of effective renal plasma flow (ERPF) can be made easily, inexpensively, and accurately by means of a single plasma concentration determination, sampled 44 min after injection of 131I-orthoiodohippurate (OIH). We originally established predictive regression equations based on a series of patients with a wide variety of diseases and a few normal potential kidney donors. The equation best fitting that data was parabolic in form and assumed a negative slope when high ERPF rates were encountered. This problem has been corrected by deriving new equations (parabolic and exponential) based on an expanded series which includes a large number of subjects with high ERPF. Errors of estimation are lower than those of the more classic para-aminohippuric acid (PAH) clearances and well within the exigencies of clinical practice. © 1982 Springer-Verlag.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 27704262
  • Author List

  • Tauxe WN; Dubovsky EV; Kidd T; Diaz F; Smith LR
  • Start Page

  • 51
  • End Page

  • 54
  • Volume

  • 7
  • Issue

  • 2