The preparation and characterization of some phosphinoacetic acids, salts, and esters

Academic Article


  • A general method is outlined for the preparation of compounds containing the -P(CH COOY) grouping, where Y - alkyl group, H, or Na and n = 1–3. This method is based on the methathesis reaction between esters of trialkylstannylacetic acids and phosphorus compounds containing a P-Cl bond. In particular, this paper reports the synthesis of the compounds (C H ) P(CH COOY) where n=1–3. These compounds were characterized by elemental analysis, melting and/or boiling points, and infrared and proton and phosphorus-31 nuclear magnetic resonance spectral data. Protonation constants for (C H) PCH COOH and C, H_P(CH C00H) were determined in ethanol-water and water, respectively. Synthesis and characterization of (CH_)„ P(0)(CH COOCH ) are reported also. © 1975, Taylor & Francis Group, LLC. All rights reserved. 2 n 6 5 3-n 2 n £ o n 2 3
  • Authors

    Digital Object Identifier (doi)

    Author List

  • Kakli MA; Gray GM; DelMar EG; Taylor RC
  • Start Page

  • 357
  • End Page

  • 371
  • Volume

  • 5
  • Issue

  • 5-6