Use of pentafluorophenyl esters for one-pot protection/activation of amino and thiol carboxylic acids

Academic Article

Abstract

  • As part of our efforts in the area of combinatorial chemistry, we have been exploring new methods for the construction of combinatorial libraries in a bidirectional fashion. Herein, we describe a new one-pot procedure for the simultaneous protection/activation of amino and thiol carboxylic acids using pentafluorophenyl trifluoroacetate (TFAPfp) and related pentafluorophenyl reagents (FmocPfp and AcPfp).
  • Digital Object Identifier (doi)

    Author List

  • Gayo LM; Suto MJ
  • Start Page

  • 4915
  • End Page

  • 4918
  • Volume

  • 37
  • Issue

  • 28