Synthesis and antiviral evaluation of analogs of adenosine-N1-oxide and 1-(benzyloxy)adenosine

Academic Article

Abstract

  • The activity of a series of compounds related to adenosine-N1-oxide (1) and 1-(benzyloxy)adenosine (42) against vaccinia virus has been determined both in vitro and in a vaccinia mouse tailpox model. Significant activities have been found both in vitro and in vivo for a number of the synthetic compounds.
  • Published In

    Digital Object Identifier (doi)

    Pubmed Id

  • 20926271
  • Author List

  • Kwong CD; Krauth CA; Shortnacy-Fowler AT; Arnett G; Hollingshead MG; Shannon WM; Montgomery JA; Secrist JA
  • Start Page

  • 1409
  • End Page

  • 1443
  • Volume

  • 17
  • Issue

  • 8