© 2017 Association for Tertiary Education Management and the LH Martin Institute for Tertiary Education Leadership and Management. Change initiatives in higher education are frequently guided by an institutional change management program which provides employees with a framework and set of skills to better understand problems and facilitate change at the organisational level. In this paper, we explore employee perceptions of Six Sigma as a tool for facilitating change at one public institution of higher education in the southeast United States. Unlike previous research studies that focused on specific results of change initiatives using Six Sigma, our research team considered how individuals, trained in the implementation of Six Sigma techniques and strategies, viewed the potential of the Six Sigma model to enact and sustain change initiatives in a higher education setting. In this case study, we describe Six Sigma as a change management program in higher education based on Lewin’s Three-Phase Model of Change.