Controlling radicals in the powerhouse: Development of mitoSOD

Academic Article

Abstract

  • Investigators in the redox biology field have long recognized the unique role mitochondrial superoxide generation plays in physiological signaling and in dysregulated bioenergetic dysfunction. Pharmacological manipulation has been challenging, and in this issue of Chemistry & Biology, Kelso and colleagues present the synthesis and characterization of a novel mitochondrial-targeted SOD mimetic, MitoSOD. © 2012 Elsevier Ltd.
  • Digital Object Identifier (doi)

    Pubmed Id

  • 17981245
  • Author List

  • Mitchell T; Chacko BK; Darley-Usmar V
  • Start Page

  • 1217
  • End Page

  • 1218
  • Volume

  • 19
  • Issue

  • 10