Bacterial vaginosis (BV) and the risk of incident gonococcal or chlamydial genital infection in a predominantly black population.

Academic Article


  • OBJECTIVE: The objective of this study was to assess in prospective data whether bacterial vaginosis (BV) is associated with gonococcal/chlamydial cervicitis. STUDY: A total of 1179 women at high risk for sexually transmitted infections was followed for a median of 3 years. Every 6 to 12 months, vaginal swabs were obtained for Gram stain, culture of microflora, and Neisseria gonorrhoeae and Chlamydia trachomatis. A Gram stain score of 7 to 10 based on the Nugent criteria categorized BV. RESULTS: Baseline BV was associated with concurrent gonococcal/chlamydial infection (adjusted odds ratio, 2.83; 95% confidence interval [CI], 1.81-4.42). However, the association between BV and subsequent, incident gonococcal/chlamydial genital infection was not significant (adjusted relative risk [RR], 1.52; 95% CI, 0.74-3.13). Dense growth of pigmented, anaerobic Gram-negative rods (adjusted RR, 1.93; 95% CI, 0.97-3.83) appeared to elevate the risk for newly acquired gonococcal/chlamydial genital infection. CONCLUSIONS: BV was common among a predominantly black group of women with concurrent gonococcal/chlamydial infection but did not elevate the risk for incident infection.
  • Authors

    Published In


  • Adolescent, Adult, African Continental Ancestry Group, Chlamydia Infections, Chlamydia trachomatis, Cohort Studies, Comorbidity, Confidence Intervals, Female, Gonorrhea, Humans, Incidence, Neisseria gonorrhoeae, Odds Ratio, Prospective Studies, United States, Vaginosis, Bacterial
  • Author List

  • Ness RB; Kip KE; Soper DE; Hillier S; Stamm CA; Sweet RL; Rice P; Richter HE
  • Start Page

  • 413
  • End Page

  • 417
  • Volume

  • 32
  • Issue

  • 7