Adolescent onset of lupus results in more aggressive disease and worse outcomes: results of a nested matched case-control study within LUMINA, a multiethnic US cohort (LUMINA LVII).

Academic Article


  • The objective of this study is to examine the clinical features and outcomes of patients with systemic lupus erythematosus (SLE) whose disease began in adolescence [juvenile-onset SLE (jSLE)] compared with adult-onset patients [adult-onset SLE (aSLE)] from a large multiethnic cohort. Systemic lupus erythematosus patients of African-American, Caucasian, or Hispanic ethnicity and >or=1 year follow-up were studied in two groups: jSLE (diagnosed at
  • Published In

  • Lupus  Journal
  • Keywords

  • Adolescent, Adult, Age of Onset, Case-Control Studies, Ethnic Groups, Female, Follow-Up Studies, Humans, Lupus Erythematosus, Systemic, Male, Middle Aged, Prevalence, Quality of Life, Socioeconomic Factors, Time Factors, United States
  • Digital Object Identifier (doi)

    Author List

  • Tucker LB; Uribe AG; Fernández M; Vilá LM; McGwin G; Apte M; Fessler BJ; Bastian HM; Reveille JD; Alarcón GS
  • Start Page

  • 314
  • End Page

  • 322
  • Volume

  • 17
  • Issue

  • 4