Fine-needle aspirates of the pancreas are increasingly being performed to obtain preoperative diagnoses of pancreatic lesions. This has also led to an increased recognition of nonductal pancreatic malignancies such as solid pseudopapillary neoplasm of the pancreas and pancreatic endocrine tumors. These tumors often show overlapping cytomorphologic features, which could lead to errors in interpretation by unsuspecting pathologists. This report describes the salient cytologic features of various nonductal pancreatic neoplasms that, if followed closely, should help avoid pitfalls in diagnoses. This discussion uses a case of solid pseudopapillary neoplasm of the pancreas diagnosed on endoscopic ultrasound-guided fine-needle aspirate as the model. © 2007 Lippincott Williams & Wilkins, Inc.