Myokymia, neuromyotonia, dermatomyositis, and voltage-gated K+ channel antibodies

Academic Article

Abstract

  • A young woman presented with facial myokymia in association with dermatomyositis. There was no evidence of peripheral neuropathy. Needle electromyography showed prominent myokymic discharges and brief neuromyotonic discharges in addition to many small-amplitude, shortduration motor unit potentials. Myokymia and dermatomyositis both responded to immunosuppressive treatment. The presence of antibodies to voltage-gated potassium channels and the association with dermatomyositis indicated an autoimmune cause for myokymia, which may have been due to reversible peripheral nerve hyperexcitability.
  • Authors

    Digital Object Identifier (doi)

    Pubmed Id

  • 19012867
  • Author List

  • Oh SJ; Alapati A; Claussen GC; Vernino S
  • Start Page

  • 757
  • End Page

  • 760
  • Volume

  • 27
  • Issue

  • 6