A radioimmunoimaging and MIRD dosimetry treatment planning program for radioimmunotherapy

Academic Article

Abstract

  • A treatment planning program for radioimmunotherapy employing quantitative Anger camera imaging and the MIRD formalism has been designed and implemented on a clinical nuclear medicine computer. Radionuclide residence times are calculated from linear, mono- and bi-exponential, and cubic spline fits to regional activity versus time curves, and radiation-absorbed dose estimates for all target organs for 131I, 67Cu, and 58 other radionuclides can be calculated. This software has been successfully applied to radioimmunotherapy of B-cell malignancies and breast adenocarcinomas.
  • Authors

    Published In

    Digital Object Identifier (doi)

    Author List

  • Erwin WD; Groch MW; Macey DJ; DeNardo GL; DeNardo SJ; Shen S
  • Start Page

  • 525
  • End Page

  • 532
  • Volume

  • 23
  • Issue

  • 4